Are you in the mood for comfort food but can’t decide between two favorites, mac and cheese and meatloaf? Why not enjoy the best of both worlds with this Mac and Cheese Meatloaf Casserole Recipe! This dish combines creamy, cheesy macaroni with savory meatloaf, creating the ultimate casserole that’s hearty, filling, and a guaranteed family favorite. This recipe is perfect for busy weeknights, potlucks, or whenever you’re craving something cozy and delicious. Let’s dive in and learn how to make this mouthwatering meal!
What is Mac and Cheese Meatloaf Casserole?
Mac and Cheese Meatloaf Casserole is exactly what it sounds like – a delightful combination of two classic dishes. On the bottom, you have a flavorful, juicy meatloaf base, and on top, a creamy layer of cheesy mac and cheese. Once baked together, the casserole forms a perfectly satisfying meal that can easily feed a crowd. It’s a mash-up that brings together the savory goodness of meatloaf with the comforting creaminess of mac and cheese, creating a dish that’s as fun to eat as it is to make!
Ingredients List for Mac and Cheese Meatloaf Casserole
To make this delicious Mac and Cheese Meatloaf Casserole, you will need the following ingredients:
For the Meatloaf Layer:
- Ground Beef (1 ½ lbs) – Lean ground beef works best to avoid excessive grease.
- Breadcrumbs (1 cup) – Plain or seasoned breadcrumbs help bind the meatloaf.
- Eggs (2 large) – Used as a binder to hold the meatloaf together.
- Onion (1 small, finely chopped) – Adds flavor and moisture to the meatloaf.
- Garlic (2 cloves, minced) – Adds a nice flavor kick to the meat.
- Ketchup (½ cup) – Adds moisture and a tangy sweetness to the meatloaf.
- Worcestershire Sauce (1 tbsp) – Adds a deep umami flavor.
- Milk (¼ cup) – Adds moisture and helps bind the meat mixture.
- Salt and Pepper (to taste) – For seasoning the meatloaf.
- Italian Seasoning (1 tsp) – Adds flavor depth to the meatloaf mixture.
- Cheddar Cheese (1 cup, shredded) – Optional but adds a cheesy element to the meatloaf layer.
For the Mac and Cheese Layer:
- Elbow Macaroni (2 cups, uncooked) – Any small pasta shape works, but elbow macaroni is traditional.
- Cheddar Cheese (2 cups, shredded) – The star of the show for a cheesy, gooey mac and cheese layer.
- Milk (2 cups) – Whole milk or 2% milk works best for creaminess.
- Butter (2 tbsp) – Adds richness to the cheese sauce.
- Flour (2 tbsp) – For thickening the cheese sauce.
- Heavy Cream (½ cup, optional) – Adds extra creaminess to the sauce.
- Salt and Pepper (to taste) – To season the cheese sauce.
- Paprika (½ tsp, optional) – Adds a hint of smokiness and color to the mac and cheese.
Substitutions and Variations
This Mac and Cheese Meatloaf Casserole is highly customizable, so feel free to make it your own with these variations:
- Ground Meat Options: If you don’t have ground beef, you can use ground turkey, chicken, or even pork. A blend of beef and pork can add extra flavor as well.
- Cheese Variations: While cheddar is classic for mac and cheese, you can use other cheeses like Monterey Jack, mozzarella, or a mix of cheeses like Gouda or Parmesan for different flavor profiles.
- Gluten-Free: To make this recipe gluten-free, use gluten-free breadcrumbs and pasta, and replace the flour in the cheese sauce with cornstarch or a gluten-free flour blend.
- Vegetable Add-ins: Add vegetables to the meatloaf layer like shredded carrots, zucchini, or bell peppers to boost the nutrition. You can also fold steamed broccoli or peas into the mac and cheese layer for extra veggies.
- Spicy Option: For a spicy twist, add a pinch of cayenne pepper or red pepper flakes to the meatloaf mixture and top the mac and cheese with sliced jalapeños.
- BBQ Meatloaf: Swap the ketchup for your favorite BBQ sauce in the meatloaf mixture for a smoky, sweet flavor.
Step-by-Step Cooking Instructions

How to Cook Mac and Cheese Meatloaf Casserole: A Step-by-Step Guide
- Preheat the Oven: Preheat your oven to 375°F (190°C). Lightly grease a 9x13-inch casserole dish or baking dish.
- Prepare the Meatloaf Layer:
- In a large mixing bowl, combine the ground beef, breadcrumbs, eggs, chopped onion, minced garlic, ketchup, Worcestershire sauce, milk, cheddar cheese (if using), and season with salt, pepper, and Italian seasoning.
- Mix everything together with your hands or a spoon until fully combined but don’t overmix.
- Press the meatloaf mixture evenly into the bottom of the prepared casserole dish to form the base layer.
- Bake the Meatloaf Base:
- Bake the meatloaf layer in the preheated oven for about 20-25 minutes, or until it is just starting to set but not fully cooked. This helps the meatloaf firm up before adding the mac and cheese layer.
- Cook the Pasta:
- While the meatloaf is baking, bring a large pot of salted water to a boil. Cook the elbow macaroni according to package instructions until al dente. Drain the pasta and set it aside.
- Make the Cheese Sauce:
- In a large saucepan, melt the butter over medium heat. Add the flour and whisk constantly for about 1-2 minutes to make a roux.
- Slowly whisk in the milk and heavy cream (if using), cooking until the mixture thickens and becomes smooth.
- Stir in the shredded cheddar cheese, paprika, salt, and pepper. Continue stirring until the cheese is fully melted and the sauce is smooth and creamy.
- Combine the Macaroni and Cheese Sauce:
- Add the cooked pasta to the cheese sauce, stirring until all the pasta is evenly coated.
- Layer the Mac and Cheese:
- Carefully spread the mac and cheese mixture over the partially cooked meatloaf layer in the casserole dish, spreading it out evenly with a spatula.
- Top with More Cheese (optional):
- If you want extra cheesy goodness, sprinkle additional shredded cheddar or your favorite cheese on top of the mac and cheese layer.
- Bake the Casserole:
- Return the casserole to the oven and bake for another 20-25 minutes, or until the top is golden brown and bubbly, and the meatloaf is fully cooked through.
- Rest and Serve:
- Once baked, let the casserole rest for about 5-10 minutes to set. Cut into squares and serve warm.
Common Mistakes to Avoid
- Overmixing the Meatloaf: When combining the meatloaf ingredients, mix just until combined. Overmixing can make the meatloaf dense and tough.
- Not Cooking the Meatloaf Layer First: Partially baking the meatloaf layer before adding the mac and cheese helps ensure the meat is fully cooked and firm.
- Overcooking the Pasta: Cook the macaroni until al dente. Overcooked pasta can become mushy once baked with the cheese sauce.
- Skipping the Resting Time: After baking, let the casserole rest for a few minutes before cutting into it. This helps the layers set and makes it easier to serve.
Serving and Presentation Tips
How to Serve Mac and Cheese Meatloaf Casserole
This casserole is hearty enough to stand alone, but pairing it with some simple sides can enhance the meal:
- Green Salad: A fresh green salad with a tangy vinaigrette helps cut through the richness of the casserole.
- Roasted Vegetables: Serve alongside roasted Brussels sprouts, carrots, or green beans for a healthy balance.
- Garlic Bread: A slice of buttery garlic bread or a dinner roll pairs perfectly with this cheesy casserole.
Presentation Ideas for Mac and Cheese Meatloaf Casserole
- Garnish: Sprinkle fresh parsley or chives on top for a pop of color and freshness.
- Family-Style Serving: Serve the casserole directly from the baking dish for a casual, homestyle meal.
- Individual Servings: For a more elegant presentation, serve the casserole in individual ramekins or small baking dishes.
Mac and Cheese Meatloaf Casserole Recipe Tips
- Make Ahead: You can assemble the casserole up to a day in advance and refrigerate it. When you’re ready to bake, just pop it in the oven for a quick dinner.
- Freezing: This casserole freezes well. Assemble the casserole, wrap it tightly, and freeze for up to 3 months. Thaw overnight in the refrigerator before baking.
- Leftovers: Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in the oven or microwave until warmed through.
Frequently Asked Questions (FAQs)
Can I use a different type of pasta for the mac and cheese layer?
Yes! While elbow macaroni is traditional, you can use any small pasta shape like penne, shells, or rotini.
Can I make this casserole ahead of time?
Absolutely. You can assemble the casserole up to a day in advance and refrigerate it. Just bake it when you're ready to serve.
Can I freeze this casserole?
Yes, this casserole freezes well. To freeze, assemble the casserole, wrap it tightly in plastic wrap and aluminum foil, and freeze for up to 3 months. Thaw in the fridge before baking.
What’s the best way to reheat leftovers?
You can reheat leftovers in the oven at 350°F until warmed through. Alternatively, you can microwave individual portions until hot.
Conclusion
This Mac and Cheese Meatloaf Casserole is the ultimate comfort food mash-up, combining two classic favorites into one delicious meal. With a juicy, flavorful meatloaf base and a creamy, cheesy mac and cheese topping, this dish is sure to become a family favorite. It’s easy to make, feeds a crowd, and is perfect for busy weeknights or potluck gatherings. Give this casserole a try and enjoy the rich, comforting flavors of mac and cheese and meatloaf all in one bite!
Happy cooking, and enjoy your cozy Mac and Cheese Meatloaf Casserole!
PrintMac and Cheese Meatloaf Casserole Recipe
Mac and Cheese Meatloaf Casserole is a comforting, two-in-one dish that combines a hearty meatloaf base with creamy, cheesy mac and cheese on top. This ultimate comfort food is ideal for satisfying cravings, combining two favorite dishes into one delicious casserole. Easy to prepare and perfect for family dinners or potlucks, this casserole is sure to be a hit!
- Prep Time: 20 minutes
- Cook Time: 40-45 minutes
- Total Time: 1 hour 5 minutes
- Yield: 6 servings 1x
- Category: Casserole
- Method: Baking
- Cuisine: American
- Diet: Gluten Free
Ingredients
- For the Meatloaf Layer:
- 1 ½ lbs ground beef
- ½ cup breadcrumbs
- 1 egg
- ¼ cup ketchup
- ¼ cup milk
- 1 tsp garlic powder
- 1 tsp onion powder
- 1 tsp Worcestershire sauce
- Salt and pepper to taste
- For the Mac and Cheese Layer:
- 2 cups elbow macaroni
- 2 cups shredded cheddar cheese
- 1 ½ cups milk
- 2 tbsp butter
- 2 tbsp all-purpose flour
- ½ tsp mustard powder
- Salt and pepper to taste
- ¼ cup breadcrumbs (optional for topping)
Instructions
- Preheat oven to 350°F (175°C).
- Make the Meatloaf Layer: In a large bowl, mix the ground beef, breadcrumbs, egg, ketchup, milk, garlic powder, onion powder, Worcestershire sauce, salt, and pepper. Press the meat mixture into the bottom of a greased 9x13-inch casserole dish, forming an even layer.
- Bake the Meatloaf: Bake for 20-25 minutes until mostly cooked through.
- Prepare the Mac and Cheese: While the meatloaf bakes, cook the macaroni according to package instructions and drain.
- In a saucepan, melt the butter over medium heat. Stir in the flour and cook for 1-2 minutes to form a roux. Slowly add the milk, whisking constantly until thickened. Stir in the mustard powder, salt, pepper, and shredded cheese until smooth and creamy.
- Mix the cooked macaroni with the cheese sauce and spoon it over the baked meatloaf layer.
- Optional: Sprinkle breadcrumbs over the mac and cheese layer for a crunchy topping.
- Final Bake: Return the casserole to the oven and bake for an additional 15-20 minutes, until the mac and cheese is bubbly and golden on top.
- Let it rest for a few minutes before serving.
Notes
- For added flavor, mix barbecue sauce with ketchup for the meatloaf.
- Use different cheeses such as mozzarella or Colby Jack for variety.
- This dish can be made ahead and baked before serving.
Nutrition
- Serving Size: 1 cup
- Calories: 580
- Sugar: 5g
- Sodium: 900mg
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